Tirzepatide

Tirzepatide is a 39-amino-acid synthetic peptide based on the native GIP sequence, modified to activate both the GIP receptor and the GLP-1 receptor. A C20 fatty diacid moiety enables albumin binding and a prolonged half-life. Tirzepatide is the active substance of licensed prescription medicines; the material supplied here is research-grade peptide and is not a medicinal product.

• Class: Dual GIP/GLP-1 receptor agonist
• Mechanisms studied: GIPR and GLP-1R activation, biased agonism at GLP-1R, insulin secretion in islet models
• Research areas: Incretin biology, pancreatic beta-cell function and adipose tissue signalling
• Sizes: 5, 10, 15, 20, 30, 40, 50, 60, 80 and 100mg lyophilised vials

All products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.