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PE-22-28

PE-22-28 is a seven-amino-acid peptide derived from spadin, a fragment of the sortilin propeptide. It inhibits the TREK-1 two-pore-domain potassium channel and was developed as a shorter, more stable analogue of spadin.

Class: Spadin-derived peptide / TREK-1 inhibitor
Mechanisms studied: TREK-1 channel inhibition, neurogenesis and synaptogenesis markers
Research areas: Mood-related and neuroplasticity models
Sizes: 5mg and 10mg lyophilised vials

All products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.

Research explained

What are research peptides?

Research peptides are short chains of amino acids studied in laboratory and preclinical research. Researchers examine how these compounds interact with biological pathways and use the findings to support further scientific investigation.

Our research peptides are supplied for laboratory research and analytical purposes only. They are not medicines, supplements, or products for human or veterinary use.