{"title":"PT-141","description":"\u003cp\u003ePT-141 (bremelanotide) is a cyclic heptapeptide melanocortin analogue related to Melanotan II. It acts mainly at the MC3 and MC4 receptors in the central nervous system. Bremelanotide is the active substance of a licensed medicine in some countries; the material supplied here is research-grade peptide.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e Melanocortin receptor agonist\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanisms studied:\u003c\/strong\u003e MC3R and MC4R activation in central nervous system signalling\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch areas:\u003c\/strong\u003e Melanocortin and neuroendocrine models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes:\u003c\/strong\u003e 10mg lyophilised vials\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eAll products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"lab-research-pt-141-peptide","title":"PT-141 - 10MG","description":"\u003cp\u003e\u003cstrong\u003ePT-141\u003c\/strong\u003e is a research product containing bremelanotide, a synthetic cyclic heptapeptide and the deamidated metabolite of Melanotan II. The single change from MT-2 – a free carboxylic acid in place of the C-terminal amide – shifts its receptor profile toward MC4R and MC3R with reduced MC1R activity, which is why the two compounds are studied for different things despite near-identical structures. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e PT-141 (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e Bremelanotide; CAS 189691-06-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational melanocortin analogue (research grade)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceptor activity:\u003c\/strong\u003e MC4R \/ MC3R agonist; reduced MC1R activity vs MT-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Central melanocortin signalling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e A pharmaceutical formulation of bremelanotide is a licensed prescription medicine in some jurisdictions. This research-grade material is not that medicine and is not manufactured to pharmaceutical standards. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841146245463,"sku":"PT141","price":19.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/peptide-stock-vial-uk.png?v=1792797914"}],"url":"https:\/\/peptidestock.co.uk\/collections\/pt-141.oembed","provider":"Peptide Stock","version":"1.0","type":"link"}