{"title":"MOTS-c","description":"\u003cp\u003eMOTS-c is a 16-amino-acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene, making it one of a small group of mitochondrial-derived peptides (described in 2015). Under metabolic stress it can move to the nucleus and influence gene expression.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e Mitochondrial-derived peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanisms studied:\u003c\/strong\u003e AMPK activation, folate cycle and AICAR accumulation, nuclear signalling under stress\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch areas:\u003c\/strong\u003e Metabolic homeostasis, exercise and ageing models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes:\u003c\/strong\u003e 10mg, 20mg and 40mg lyophilised vials\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eAll products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"lab-research-mots-c-peptide","title":"MOTS-c 40mg","description":"\u003cp\u003e\u003cstrong\u003eMOTS-c\u003c\/strong\u003e is a research product containing a 16-amino-acid peptide encoded within the mitochondrial genome (the 12S rRNA region), one of a small family of mitochondrial-derived peptides identified in the last decade. It is studied in mouse and cell-culture models for its role in metabolic homeostasis, acting through the folate–methionine cycle and AMPK signalling, and for its response to exercise and metabolic stress. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e MOTS-c (mitochondrial ORF of the 12S rRNA type-c)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e CAS 1627580-64-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 40mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational mitochondrial-derived peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism studied:\u003c\/strong\u003e AMPK activation; folate–methionine cycle; nuclear translocation under stress\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Metabolic homeostasis and ageing models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e MOTS-c is a preclinical research compound and not an approved medicine. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841146671447,"sku":"MS40","price":34.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/CobaltBlueMOTS-cPeptideVial.png?v=1792774529"},{"product_id":"lab-research-mots-c-peptide-10mg","title":"MOTS-c 10mg","description":"\u003cp\u003e\u003cstrong\u003eMOTS-c\u003c\/strong\u003e is a research product containing a 16-amino-acid peptide encoded within the mitochondrial genome (the 12S rRNA region), one of a small family of mitochondrial-derived peptides identified in the last decade. It is studied in mouse and cell-culture models for its role in metabolic homeostasis, acting through the folate–methionine cycle and AMPK signalling, and for its response to exercise and metabolic stress. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e MOTS-c (mitochondrial ORF of the 12S rRNA type-c)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e CAS 1627580-64-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational mitochondrial-derived peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism studied:\u003c\/strong\u003e AMPK activation; folate–methionine cycle; nuclear translocation under stress\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Metabolic homeostasis and ageing models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e MOTS-c is a preclinical research compound and not an approved medicine. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":55077829902679,"sku":"MS10","price":18.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/MOTS-cPeptideVialProductShot.png?v=1792774630"},{"product_id":"lab-research-mots-c-peptide-20mg","title":"MOTS-C 20mg","description":"\u003cp\u003e\u003cstrong\u003eMOTS-c\u003c\/strong\u003e is a research product containing a 16-amino-acid peptide encoded within the mitochondrial genome (the 12S rRNA region), one of a small family of mitochondrial-derived peptides identified in the last decade. It is studied in mouse and cell-culture models for its role in metabolic homeostasis, acting through the folate–methionine cycle and AMPK signalling, and for its response to exercise and metabolic stress. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e MOTS-c (mitochondrial ORF of the 12S rRNA type-c)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e CAS 1627580-64-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 20mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational mitochondrial-derived peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism studied:\u003c\/strong\u003e AMPK activation; folate–methionine cycle; nuclear translocation under stress\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Metabolic homeostasis and ageing models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e MOTS-c is a preclinical research compound and not an approved medicine. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":55478515499351,"sku":"MS20","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/Blue-CappedMOTS-cPeptideVial.png?v=1792774591"}],"url":"https:\/\/peptidestock.co.uk\/collections\/mots-c.oembed","provider":"Peptide Stock","version":"1.0","type":"link"}