{"title":"Melanotan","description":"\u003cp\u003eMelanotan I and Melanotan II are synthetic analogues of alpha-melanocyte-stimulating hormone (α-MSH). Melanotan I (afamelanotide, [Nle4, D-Phe7]-α-MSH) is a linear peptide that acts mainly at the MC1 receptor and is the active substance of a licensed medicine. Melanotan II is a shorter cyclic peptide that acts at several melanocortin receptors (MC1R, MC3R, MC4R and MC5R). The material supplied here is research-grade peptide.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e Melanocortin receptor agonists\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanisms studied:\u003c\/strong\u003e MC1R-driven melanogenesis and wider melanocortin receptor signalling\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch areas:\u003c\/strong\u003e Melanocyte and pigmentation models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes:\u003c\/strong\u003e Melanotan I 10mg and Melanotan II 10mg lyophilised vials\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eAll products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"lab-research-mt-1-peptide","title":"MT-1 10mg","description":"\u003cp\u003e\u003cstrong\u003eMelanotan I\u003c\/strong\u003e is a research product containing afamelanotide, a linear 13-amino-acid analogue of alpha-melanocyte-stimulating hormone with two substitutions – norleucine at position 4 and D-phenylalanine at position 7 – that extend its half-life relative to the native hormone. Unlike Melanotan II it is not cyclised and is more selective for MC1R, making it the cleaner tool compound for melanocyte and pigmentation research. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Melanotan I ([Nle\u003csup\u003e4\u003c\/sup\u003e, D-Phe\u003csup\u003e7\u003c\/sup\u003e]-α-MSH)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e Afamelanotide; MT-1; CAS 75921-69-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational melanocortin analogue (research grade)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceptor activity:\u003c\/strong\u003e MC1R-selective agonist\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Melanocyte biology and pigmentation models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e A pharmaceutical implant formulation of afamelanotide is a licensed prescription medicine in the UK and EU. This research-grade material is not that medicine and is not manufactured to pharmaceutical standards. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841146605911,"sku":"MT-1","price":17.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/peptide-stock-vial-uk.png?v=1792797914"},{"product_id":"lab-research-mt-2-peptide","title":"MT-2 10mg","description":"\u003cp\u003e\u003cstrong\u003eMelanotan II\u003c\/strong\u003e is a research product containing a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone, developed in the 1980s at the University of Arizona. A D-phenylalanine substitution and a lactam bridge make it far more stable and potent than native α-MSH, and it is a non-selective agonist across the melanocortin receptor family. It is the reference compound for MC1R-mediated melanogenesis research and the parent molecule of PT-141. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH\u003csub\u003e2\u003c\/sub\u003e)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e MT-2; MT-II; CAS 121062-08-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational melanocortin analogue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceptor activity:\u003c\/strong\u003e Non-selective MC1R \/ MC3R \/ MC4R \/ MC5R agonist\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Melanogenesis and melanocortin receptor pharmacology\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Melanotan II has never been approved as a medicine in any jurisdiction and the MHRA has issued public warnings about unlicensed use. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841147392343,"sku":"MT-2","price":14.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/peptide-stock-vial-uk.png?v=1792797914"}],"url":"https:\/\/peptidestock.co.uk\/collections\/melanotan.oembed","provider":"Peptide Stock","version":"1.0","type":"link"}