{"title":"IGF-1 LR3","description":"\u003cp\u003eIGF-1 LR3 is an 83-amino-acid analogue of insulin-like growth factor 1 with arginine in place of glutamic acid at position 3 and a 13-amino-acid N-terminal extension. These changes greatly reduce binding to IGF-binding proteins, prolonging its activity, and it is widely used as a growth-factor supplement in cell culture.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e IGF-1 analogue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanisms studied:\u003c\/strong\u003e IGF-1 receptor activation, PI3K\/Akt and MAPK signalling\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch areas:\u003c\/strong\u003e Cell proliferation, muscle-cell and cell-culture models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes:\u003c\/strong\u003e 0.1mg and 1mg lyophilised vials\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eAll products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"lab-research-igf1lr3-peptide","title":"IGF1LR3 1MG","description":"\u003cp\u003e\u003cstrong\u003eIGF-1 LR3\u003c\/strong\u003e is a research product containing Long R3 IGF-1, an 83-amino-acid analogue of insulin-like growth factor-1 with an arginine substitution at position 3 and a 13-residue N-terminal extension. Those modifications sharply reduce its binding to IGF-binding proteins, which extends its active half-life in vitro and makes it the standard form of IGF-1 used as a growth-factor supplement in cell-culture media and in IGF-1 receptor signalling research. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Long R3 IGF-1 (recombinant)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e LR3-IGF-1; CAS 946870-92-4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 1mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Recombinant growth-factor analogue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceptor activity:\u003c\/strong\u003e IGF-1 receptor agonist; low IGFBP affinity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Cell-culture supplementation and IGF-1R signalling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e IGF-1 LR3 is a laboratory reagent and not an approved medicine. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841146310999,"sku":"IG01","price":34.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/peptide-stock-vial-uk.png?v=1792797914"},{"product_id":"lab-research-igf1lr3-peptide-0-1mg","title":"IGF-1 LR3 0.1mg","description":null,"brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":55552304972119,"sku":"IG0.1","price":14.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/peptide-stock-vial-uk.png?v=1792797914"}],"url":"https:\/\/peptidestock.co.uk\/collections\/igf-1-lr3.oembed","provider":"Peptide Stock","version":"1.0","type":"link"}