{"title":"5-Amino-1MQ","description":"\u003cp\u003e5-Amino-1-methylquinolinium (5-Amino-1MQ) is a membrane-permeable small molecule rather than a peptide. It inhibits nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide and influences the NAD+ salvage pathway and the cellular methyl-donor pool.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e Small-molecule NNMT inhibitor\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanisms studied:\u003c\/strong\u003e NNMT inhibition, NAD+ salvage and SAM\/methylation balance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch areas:\u003c\/strong\u003e Adipocyte metabolism and cellular energy regulation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes:\u003c\/strong\u003e 5mg, 10mg and 50mg\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eAll products are supplied for in vitro laboratory research only. Not for human or veterinary use. No dosing or protocol guidance is provided.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"lab-research-5amino-peptide","title":"5-Amino-1MQ 50mg","description":"\u003cp\u003e\u003cstrong\u003e5-Amino-1MQ\u003c\/strong\u003e is a research product containing 5-amino-1-methylquinolinium, a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). It is not a peptide. NNMT is an enzyme that consumes both nicotinamide and S-adenosylmethionine, and its activity is elevated in adipose tissue in several rodent models of metabolic dysfunction; 5-Amino-1MQ is the standard membrane-permeable tool compound for studying that pathway. The product information should be reviewed alongside appropriate research documentation and should not be presented as an approved medicine. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e 5-Amino-1-methylquinolinium\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative identifier:\u003c\/strong\u003e 5-Amino-1MQ; CAS 42464-96-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity per vial:\u003c\/strong\u003e 50mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder, sealed vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Investigational small-molecule enzyme inhibitor\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism studied:\u003c\/strong\u003e Selective NNMT inhibition\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch area:\u003c\/strong\u003e Adipocyte metabolism and NAD+ salvage pathway models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e 5-Amino-1MQ is a preclinical research chemical and not an approved medicine. Supplied for laboratory research only; not for human or veterinary use.\u003c\/p\u003e","brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":54841145885015,"sku":"50AM","price":25.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/Blue-CappedPeptideStockVial_1.png?v=1792709811"},{"product_id":"lab-research-5amino-peptide-5mg","title":"5-Amino-1MQ 5mg","description":null,"brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":55478477193559,"sku":"5AM05","price":14.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/Blue-CappedPeptideStockVial_1.png?v=1792709811"},{"product_id":"lab-research-5amino-peptide-10mg","title":"5-Amino-1MQ 10mg","description":null,"brand":"Peptide Stock","offers":[{"title":"Default Title","offer_id":55478477291863,"sku":"5AM10","price":19.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1044\/0304\/2647\/files\/Blue-CappedPeptideStockVial_1.png?v=1792709811"}],"url":"https:\/\/peptidestock.co.uk\/collections\/5-amino-1mq.oembed","provider":"Peptide Stock","version":"1.0","type":"link"}